There has been recent changes in Vina web services that makes it impossible to run Vina in Remote (Opal Web Services) mode. I've uploaded new updates to fix this.  Please use PyRx > Help > Check for Updates... menu to apply this update if you are using Linux or PyRx 0.9.7 or higher on Windows. Unfortunately PyRx update procedure doesn't work on Mac OS X or on Windows with PyRx 0.9.6 and earlier versions. Please use the following steps to update PyRx instead.

Step 1, visit https://sourceforge.net/p/pyrx/code/HEAD/tree/PyRxDev/ and click on Download Snapshot.

Step 2, uncompress this downloaded file and locate PyRxDev/PyRx folder.

Step 3, make a backup copy of the following folder, by renaming it to PyRx.bak for instance, in case PyRx fails to start after this update:

• Windows PyRx 0.9.6 or earlier - C:\Program Files (x86)\PyRx\$Version\Lib\site-packages\PyRx
• Windows PyRx 0.9.7 or older - C:\Program Files\PyRx\$Version\Lib\site-packages\PyRx
• Mac OS X - /Library/PyRx/$Version/Python.framework/Versions/2.6/lib/python2.6/site-packages/PyRx

$Version here is the version number of PyRx (e.g. 0.9.6)

Step 4, replace this folder with the one you downloaded above.

If you have updated PyRx previously using Help > Check for Updates... menu, delete .PyRx_workspace\update from your home directory.

Please let me know if you have questions or need more information.